SR 142948 (Standard), CAS [[184162-64-9]] Preis auf Anfrage
Artikelnummer:
MCE-HY-107664R
Hersteller Artikelnummer:
HY-107664R
Alternativnummer:
MCE-HY-107664R-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
SR 142948 (Standard) is the analytical standard of SR 142948 (HY-107664). This product is intended for research and analytical applications. SR 142948 is an orally active and selective non-peptide neurotensin receptor (NT) antagonist with IC50s of 1.19 nM, 0.32 nM, 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. SR 142948 antagonizes NT-induced inositol monophosphate formation in HT-29 cells with an IC50 of 3.9 nM. SR 142948 blocks hypothermia, analgesia and steering behavior induced by NT in vivo. SR 142948 shows blood-brain permeability and can be used in study of psychiatric disorders[1][2].
Molekulargewicht:
685.85
CAS Nummer:
[184162-64-9]
Formel:
C39H51N5O6
Target-Kategorie:
Neurotensin Receptor,Reference Standards
Anwendungsbeschreibung:
MCE Product type: Reference Standards
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