JNJ-5207787 is a nonpeptidic, selective and penetrate the blood-brain barrier neuropeptide Y Y2 receptor (Y2) antagonist. JNJ-5207787 inhibits the binding of peptide YY (PYY) with pIC50s of 7.0 and 7.1 for human Y2 receptor and rat Y2 receptor, respectively. JNJ-5207787 is >100-fold selective versus human Y1, Y4, and Y5 receptors[1].
Molekulargewicht:
510.67
Reinheit:
98.00
CAS Nummer:
[683746-68-1]
Formel:
C32H38N4O2
Target-Kategorie:
Neuropeptide Y Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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