Guggulsterone, CAS [[95975-55-6]]

Produktübersicht

• Artikelname: Guggulsterone, CAS [[95975-55-6]]
• Artikelnummer: MCE-HY-107738
• Hersteller Artikelnummer: HY-107738
• Alternativnummer: MCE-HY-107738-10MMX1ML,MCE-HY-107738-100MG,MCE-HY-107738-50MG,MCE-HY-107738-10MG,MCE-HY-107738-25MG,MCE-HY-107738-5MG,MCE-HY-107738-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: Z/E-Guggulsterone

Produktbeschreibung

Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt[1][2]. Guggulsterone, a farnesoid X receptor (FXR) antagonist, with IC50s of 24.06 µM and 39.05 µM for (-)-(E)-Guggulsterone (HY-N7781) and (Z)-Guggulsterone (HY-110066), respectively[3].

Produkteigenschaften

• Molekulargewicht: 312.45
• Reinheit: 99.83
• CAS Nummer: [95975-55-6]
• Formel: C21H28O2
• Target-Kategorie: Akt,Apoptosis,Autophagy,Caspase,FXR,JNK

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Natural Products