SB-237376 (free base), CAS [[179258-59-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: SB-237376 (free base), CAS [[179258-59-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-108163
• Hersteller Artikelnummer: HY-108163
• Alternativnummer: MCE-HY-108163-1MG,MCE-HY-108163-10MG,MCE-HY-108163-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

SB-237376 (free base) is a potassium and calcium channel blocker. SB-237376 (free base) can inhibit the rapidly activating delayed rectifier potassium current I(Kr) (IC50 is 0.42 µM), and at high concentrations, it blocks the L-type calcium current I(Ca,L). In the rabbit ventricular model, SB-237376 (free base) can induce early afterdepolarizations (EADs) at a concentration of 3 µM. Compared to other IKr inhibitors such as dl-sotalol, SB-237376 has a lower proarrhythmic risk. SB-237376 (free base) holds potential for research in the field of arrhythmia-related diseases[1].

Produkteigenschaften

• Molekulargewicht: 387.43
• CAS Nummer: [179258-59-4]
• Formel: C20H25N3O5
• Target-Kategorie: Calcium Channel,Potassium Channel

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound