BIX-01294 trihydrochloride (Standard), CAS [[1392399-03-9]] Preis auf Anfrage
Artikelnummer:
MCE-HY-108239R
Hersteller Artikelnummer:
HY-108239R
Alternativnummer:
MCE-HY-108239R-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
BIX-01294 trihydrochloride (Standard) is the analytical standard of BIX-01294 (trihydrochloride) (HY-108239). This product is intended for research and analytical applications. BIX-01294 trihydrochloride is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 µM and 0.9 µM, respectively. BIX-01294 trihydrochloride inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294 trihydrochloride, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 trihydrochloride has antitumor activity in recurrent tumor cells[1][2][3][4][5].
