Propacetamol hydrochloride is an orally active prodrug of paracetamol and an inducer of acute liver injury models, with multiple properties including antinociception, antioxidation and gastroprotection. Propacetamol hydrochloride potentiates Tramadol and attenuates Aspirin (HY-14654)-induced gastric mucosal damage and lipid peroxidation. Under specific conditions, Propacetamol hydrochloride also acts as a hepatotoxic inducer, triggering acute liver injury, oxidative stress and apoptosis, with strain differences in toxicity sensitivity. Propacetamol hydrochloride can be used in the research of acute liver injury, drug-induced hepatotoxicity and gastric mucosal damage[1][2][3][4][5].
Molekulargewicht:
300.79
Reinheit:
99.89
CAS Nummer:
[66532-86-3]
Formel:
C14H21ClN2O3
Target-Kategorie:
Others
Anwendungsbeschreibung:
MCE Product type: Reference compound
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