Alsterpaullone, CAS [[237430-03-4]]

Produktübersicht

• Artikelname: Alsterpaullone, CAS [[237430-03-4]]
• Artikelnummer: MCE-HY-108359
• Hersteller Artikelnummer: HY-108359
• Alternativnummer: MCE-HY-108359-100MG,MCE-HY-108359-50MG,MCE-HY-108359-25MG,MCE-HY-108359-5MG,MCE-HY-108359-1MG,MCE-HY-108359-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: 9-Nitropaullone, NSC 705701

Produktbeschreibung

Alsterpaullone (9-Nitropaullone) is a potent CDK inhibitor, with IC50s of 35 nM, 15 nM, 200 nM and 40 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E and CDK5/p35, respectively. Alsterpaullone also competes with ATP for binding to GSK-3alpha/GSK-3beta with IC50s of both 4 nM. Alsterpaullone has antitumor activity, and possesses potential for the study in neurodegenerative and proliferative disorders[1]. Alsterpaullone induces apoptosis in leukemia cell line[2].

Produkteigenschaften

• Molekulargewicht: 293.28
• Reinheit: 99.85
• CAS Nummer: [237430-03-4]
• Formel: C16H11N3O3
• Target-Kategorie: Apoptosis,CDK,GSK-3

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound