D3/5-HT receptor modulator-1 (compound 5i) is a selective dopamine D3 receptor and 5-HT2A receptor antagonist and a partial 5-HT1A receptor agonist. D3/5-HT receptor modulator-1 shows Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for dopamine D3, 5-HT2A, and 5-HT2A receptors. D3/5-HT receptor modulator-1 has a low affinity for dopamine D2 receptors, 5-HT2C receptors, and hERG channels. D3/5-HT receptor modulator-1 has an atypical antipsychotic profile[1].
Molekulargewicht:
391.51
Reinheit:
99.75
CAS Nummer:
[898532-85-9]
Formel:
C24H29N3O2
Target-Kategorie:
5-HT Receptor,Dopamine Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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