Mocravimod, CAS [[509092-16-4]] Preis auf Anfrage

Artikelnummer: MCE-HY-109038
Artikelname: Mocravimod, CAS [[509092-16-4]] Preis auf Anfrage
Artikelnummer: MCE-HY-109038
Hersteller Artikelnummer: HY-109038
Alternativnummer: MCE-HY-109038-25MG,MCE-HY-109038-10MG,MCE-HY-109038-50MG,MCE-HY-109038-100MG,MCE-HY-109038-5MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: KRP-203 (free base)
Mocravimod is an orally active sphingosine-1-phosphate receptor (S1PR) modulator that blocks the signal required by T cells to egress from lymph nodes and other lymphoid organs. Mocravimod preferentially binds to S1PR1 over S1PR2 and S1PR3 in cardiomyocytes. Mocravimod significantly lowered the concentration of reactive oxygen species (ROS), prevented mitochondrial permeability transition pore opening, boosted mitochondrial membrane potential (MMP), and increased phosphorylation of AKT, EKR, GSK-3beta, JAK2, and STAT3. Mocravimod retains T cell effector function. Mocravimod can be used for the study of acute myelogenous leukemia, diabetes and Myocardial Ischemia-Reperfusion Injury (MIRI)[1][2][3][4].
Molekulargewicht: 443.99
Reinheit: 98.39
CAS Nummer: [509092-16-4]
Formel: C24H26ClNO3S
Target-Kategorie: Akt,GSK-3,JAK,LPL Receptor,Reactive Oxygen Species (ROS),STAT
Anwendungsbeschreibung: MCE Product type: Reference compound