Quilseconazole (VT-1129) is an orally active, highly selective fungal cytochrome P450 enzyme Cyp51 inhibitor that can cross the blood-brain barrier. Quilseconazole prevents the synthesis of ergosterol, an important component of the fungal cell membrane, by inhibiting Cyp51. Quilseconazole has minimal effects on human CYP enzymes. Quilseconazole has antifungal activity and can be used in the study of cryptococcal meningitis and other diseases[1][2][3].
Molekulargewicht:
513.37
Reinheit:
98.61
CAS Nummer:
[1340593-70-5]
Formel:
C22H14F7N5O2
Target-Kategorie:
Cytochrome P450,Fungal
Anwendungsbeschreibung:
Reference compound
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