Upacicalcet, CAS [[1333218-50-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: Upacicalcet, CAS [[1333218-50-0]] Preis auf Anfrage
• Artikelnummer: MCE-HY-109106
• Hersteller Artikelnummer: HY-109106
• Alternativnummer: MCE-HY-109106-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: SK-1403 (free acid), AJT240 (free acid), PLS240 (free acid)

Produktbeschreibung

Upacicalcet is a non-peptide calcimimetic that acts as a CaSR agonist (EC50 = 10.8 nM). Upacicalcet reduces serum intact parathyroid hormone (iPTH) and serum Ca2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet is useful for studying SHPT[1][2].

Produkteigenschaften

• Molekulargewicht: 351.76
• CAS Nummer: [1333218-50-0]
• Formel: C11H14ClN3O6S
• Target-Kategorie: CaSR

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound