(R)-Citalopram oxalate is an anticonvulsant, antidepressant and muscle relaxant. (R)-Citalopram oxalate is at least 20-fold weaker than S-citalopram (Escitalopram, HY-14258) as inhibitor of the 5-HT transporter (SERT). (R)-Citalopram oxalate functionally antagonises S-citalopram in vivo and in vitro. (R)-Citalopram oxalate has an effect on the association of Escitalopram with the high affinity primary site, and on its dissociation from the 5-HT transporter, via an allosteric mechanism[1].
Molekulargewicht:
414.43
Reinheit:
99.52
CAS Nummer:
[219861-53-7]
Formel:
C22H23FN2O5
Target-Kategorie:
5-HT Receptor,Serotonin Transporter
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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