A-425619 is an orally active and selective transient receptor potential type V1 (TRPV1) antagonist. A-425619 blocks Capsaicin (HY-10448)- and N-arachidonoyl-dopamine (NADA)-induced Ca2+ influx in dorsal root ganglia and trigeminal ganglia. A-425619 relieves pathophysiological pain associated with inflammation and tissue injury in rats. A-425619 can be used for the study of pain related to inflammation and tissue injury[1][2][3].
Molekulargewicht:
345.32
Reinheit:
99.96
CAS Nummer:
[581809-67-8]
Formel:
C18H14F3N3O
Target-Kategorie:
Calcium Channel,TRP Channel
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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