QAQ dichloride, a photoswitchable voltage-gated Nav and Kv channels blocker, blocks channels in its trans form (of the azobenzene photoswitch), but not in its cis form. QAQ dichloride is membrane-impermeant and only infiltrates pain-sensing neurons that express endogenous import channels. QAQ dichloride acts as a light-sensitive analgesic and can be used for studying of signaling mechanisms in acute and chronic pain[1][2].
Molekulargewicht:
567.59
Reinheit:
98.68
Formel:
C28H44Cl2N6O2
Target-Kategorie:
Sodium Channel
Anwendungsbeschreibung:
MCE Product type: Reference compound
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