GR148672X, CAS [[263890-70-6]]

Produktübersicht

• Artikelname: GR148672X, CAS [[263890-70-6]]
• Artikelnummer: MCE-HY-110390
• Hersteller Artikelnummer: HY-110390
• Alternativnummer: MCE-HY-110390-5MG,MCE-HY-110390-10MG,MCE-HY-110390-50MG,MCE-HY-110390-100MG,MCE-HY-110390-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

GR148672X is an inhibitor of carboxylesterase 1 (CES1) and hepatic microsomal triglyceride hydrolase (TGH). GR148672X blocks the catalytic activity of CES1, impairs the functions of triglyceride and cholesteryl ester lipase, reduces triglyceride mobilization and secretion, and decreases apolipoprotein B-100 secretion in primary rat hepatocytes. Under low-glucose conditions, GR148672X inhibits the survival of colorectal cancer cells by reducing free fatty acid availability, inducing toxic triglyceride accumulation, ROS production, mitochondrial damage, ferroptosis and apoptosis. GR148672X can be used in studies related to colorectal cancer and atherosclerosis[1][2].

Produkteigenschaften

• Molekulargewicht: 340.32
• Reinheit: 99.58
• CAS Nummer: [263890-70-6]
• Formel: C15H11F3N2O2S
• Target-Kategorie: Apoptosis,Carboxylesterase (CES),Ferroptosis,Free Fatty Acid Receptor,Mitochondrial Metabolism,Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound