UK122 hydrochloride is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0.2 µM. UK122 hydrochloride shows no or little inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC50s > 100 µM). UK122 hydrochloride, a 4-oxazolidinone analogue, is an anticancer agent and inhibits cancer cell migration and invasion[1].
Molekulargewicht:
327.76
Reinheit:
99.43
Formel:
C17H14ClN3O2
Target-Kategorie:
Ser/Thr Protease
Anwendungsbeschreibung:
MCE Product type: Reference compound
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