Declopramide (3-Chloroprocainamide) is an orally active antitumor agent, which inhibits proliferation of cancer cells HL60 and K562, and inhibits tumor growth of human brain astrocytoma (T24) in mouse model. Declopramide induces apoptosis, inhibits NF-kappaB through inhibition of IkappaBalpha degradation. Declopramide serves also as chemosensitizer in research[1][2][3].
Molekulargewicht:
269.77
CAS Nummer:
[891-60-1]
Formel:
C13H20ClN3O
Target-Kategorie:
Apoptosis,NF-kappaB
Anwendungsbeschreibung:
MCE Product type: Reference compound
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