SV 293 is a selective antagonist with neutral antagonist activity. SV 293 binds to human D2 receptors with 100-fold higher affinity and has lower affinity for human D3 and D4 dopamine receptor subtypes. SV 293 was found to block the effects of the full agonist quinpirole in forskolin-dependent adenylate acylase inhibition assays and electrophysiological assays. SV 293 can be used as a useful pharmacological tool to study the role of dopamine D2-like receptor subtypes in dopamine pathways associated with neurological, neuropsychiatric and movement disorders[1].
Molekulargewicht:
382.52
CAS Nummer:
[873445-73-9]
Formel:
C22H26N2O2S
Target-Kategorie:
Dopamine Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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