RapaLink-1, CAS [[1887095-82-0]]

Produktübersicht

• Artikelname: RapaLink-1, CAS [[1887095-82-0]]
• Artikelnummer: MCE-HY-111373
• Hersteller Artikelnummer: HY-111373
• Alternativnummer: MCE-HY-111373-1MG,MCE-HY-111373-100MG,MCE-HY-111373-10MMX1ML,MCE-HY-111373-5MG,MCE-HY-111373-25MG,MCE-HY-111373-10MG,MCE-HY-111373-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

RapaLink-1, the third-generation bivalent mTOR inhibitor, combines Rapamycin (HY-10219) with MLN0128 (HY-13328, a second-generation mTOR kinase inhibitor) by an inert chemical linker. RapaLink-1 shows better efficacy than Rapamycin or mTOR kinase inhibitors (TORKi), potently blocking cancer-derived, activating mutants of mTOR. RapaLink-1 can cross the blood-brain barrier. RapaLink-1 binding to FKBP12 results in targeted and durable inhibition of mTORC1. RapaLink-1 plays an antithrombotic role in antiphospholipid syndrome by improving autophagy. Anticancer activity[1][2].

Produkteigenschaften

• Molekulargewicht: 1784.14
• Reinheit: 99.65
• CAS Nummer: [1887095-82-0]
• Formel: C91H138N12O24
• Target-Kategorie: Autophagy,mTOR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound