UAA crosslinker 1 hydrochloride is an amber codon used for non-canonical amino acids (ncAAs) incorporation. The ncAAs can be incorporated into proteins in vivo by making use of the promiscuous activity of certain wildtype and engineered aminoacyl-tRNA synthetases[1]. UAA crosslinker 1 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Molekulargewicht:
259.26
Reinheit:
98
CAS Nummer:
[1167421-25-1]
Formel:
C9H17N5O4
Target-Kategorie:
Biochemical Assay Reagents
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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