IQM-266 is a Downstream Regulatory Element Antagonist Modulator (DREAM) ligand with a KD of 4.63 µM. IQM-266 inhibits the KV4.3/DREAM current in a concentration-, voltage-, and time-dependent-manner. IQM-266 also modulates A-type outward potassium currents (IA) from rat dorsal root ganglia (DRG) neurons. IQM-266 can be used for neurological disease research, such as Alzheimers disease and Huntingtons disease (HD)[1].
Molekulargewicht:
397.42
Reinheit:
99.42
CAS Nummer:
[1956337-58-8]
Formel:
C25H19NO4
Target-Kategorie:
Potassium Channel
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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