WDR5-IN-4 (Compound C6) is a WIN site inhibitor of chromatin-associated WD repeat domain 5 protein (WDR5), Kd The value is 0.1 nM. WDR5-IN-4 is able to displace WDR5 from chromatin and reduce the expression of related genes, causing translation inhibition and nucleolar stress. Has anti-cancer effects [1][1].
Molekulargewicht:
498.38
Reinheit:
98.13
CAS Nummer:
[2407457-36-5]
Formel:
C25H22Cl2FN5O
Target-Kategorie:
Apoptosis,WDR5
Anwendungsbeschreibung:
MCE Product type: Reference compound
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