AZ31 is a a potent, highly selective, and orally active ATM inhibitor with an IC50 of IC50 of 46 nM for ATM in cell. AZ31 shows excellent selectivity over ATR (>500-fold) and excellent PIKK-family selectivity and pan-kinase selectivity. AZ31 is a potent radiosensitizer in vitro, it can be used for the research of cancer[1].
Molekulargewicht:
420.50
Reinheit:
98.22
CAS Nummer:
[2088113-98-6]
Formel:
C24H28N4O3
Target-Kategorie:
ATM/ATR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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