CDK12-IN-2, CAS [[2244987-03-7]]

Produktübersicht

• Artikelname: CDK12-IN-2, CAS [[2244987-03-7]]
• Artikelnummer: MCE-HY-112626
• Hersteller Artikelnummer: HY-112626
• Alternativnummer: MCE-HY-112626-10MMX1ML,MCE-HY-112626-10MG,MCE-HY-112626-50MG,MCE-HY-112626-100MG,MCE-HY-112626-25MG,MCE-HY-112626-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

CDK12-IN-2 is a potent, selective and nanomolar CDK12 inhibitor (IC50=52 nM) with good physicochemical properties. CDK12-IN-2 is also a strong CDK13 inhibitor due to CDK13 is the closest homologue of CDK12. CDK12-IN-2 shows excellent kinase selectivity for CDK12 over CDK2, 9, 8, and 7. CDK12-IN-2 inhibits the phosphorylation of Ser2 in the C-terminal domain of RNA polymerase II. CDK12-IN-2 can be used an excellent chemical probe for functional studies of CDK12[1].

Produkteigenschaften

• Molekulargewicht: 532.64
• Reinheit: 99.36
• CAS Nummer: [2244987-03-7]
• Formel: C32H32N6O2
• Target-Kategorie: CDK

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound