ME-344 is an Isoflavone. ME-344 increases mitochondrial ROS generation. ME-344 inhibits tubulin polymerization. ME-344 inhibits HO-1 and impacts its mitochondrial translocation. ME-344 induces Apoptosis through Caspase 3 activation. ME-344 synergizes with Vinblastine in leukemia cells. ME-344 displays anti-tumor activity against leukemia and lung tumor. ME-344 can be used in the research of lung cancer, acute myeloid leukemia, and HER2-negative breast cancer[1][2][3][4].
Molekulargewicht:
348.39
Reinheit:
98.12
CAS Nummer:
[1374524-68-1]
Formel:
C22H20O4
Target-Kategorie:
Apoptosis,Caspase,Heme Oxygenase (HO),Microtubule/Tubulin,Mitochondrial Metabolism,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten