(3S,4R)-ME-344, CAS [[1374524-84-1]]

Artikelnummer: MCE-HY-112749B
Artikelname: (3S,4R)-ME-344, CAS [[1374524-84-1]]
Artikelnummer: MCE-HY-112749B
Hersteller Artikelnummer: HY-112749B
Alternativnummer: MCE-HY-112749B-50MG,MCE-HY-112749B-10MG,MCE-HY-112749B-25MG,MCE-HY-112749B-5MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
(3S,4R)-ME-344 is the (3S,4R)-enantiomer of ME-344 (HY-112749). ME-344 is a mitochondrial Heme oxygenase 1 (HO-1) inhibitor. ME-344 specifically binds and alters HO-1 structure, and increases HO-1 translocation from the rough endoplasmic reticulum to mitochondria, but only in drug-sensitive cells (such as H460 and SHP-77 cells). ME-344 decreases mitochondrial ATP production and induces ROS, with subsequent disruption of redox homeostasis and mitochondrial function. ME-344 has significant antitumor activity, and can be used for cancers like breast cancer research[1].
Molekulargewicht: 348.39
Reinheit: 98.04
CAS Nummer: [1374524-84-1]
Formel: C22H20O4
Target-Kategorie: Heme Oxygenase (HO),Mitochondrial Metabolism,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung: MCE Product type: Reference compound