IBS008738 is a potent TAZ activator. IBS008738 stabilizes TAZ, increases the unphosphorylated TAZ level, enhances the association of MyoD with the myogenin promoter, upregulates MyoD-dependent gene transcription, and competes with myostatin in C2C12 cells. IBS008738 enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model[1][2].
Molekulargewicht:
374.44
Reinheit:
98.22
CAS Nummer:
[385425-03-6]
Formel:
C22H22N4O2
Target-Kategorie:
YAP
Anwendungsbeschreibung:
MCE Product type: Reference compound
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