Guanosine 5-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5-diphosphate disodium salt activates adenosine 5-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI)[1][2][3][4][5].
Molekulargewicht:
487.16
Reinheit:
99
CAS Nummer:
[7415-69-2]
Formel:
C10H13N5Na2O11P2
Target-Kategorie:
Endogenous Metabolite,Hepcidin,Potassium Channel
Anwendungsbeschreibung:
MCE Product type: Oligonucleotides
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
