Estrone sulfate potassium is an inactive endogenous estrogen that can be converted into Estrone (HY-B0234) and Estradiol (HY-B0141). Estrone sulfate potassium is also a substrate of the OATP1B3 transporter. Estrone sulfate potassium can be converted into Estrone and Estradiol in normal mammary parenchymal cells. Estrone sulfate potassium stimulates the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and the colony formation of dispersed nitrosomethylurea mammary cells, with conversion into Estrone and Estradiol occurring both in vivo and in vitro during this process. Estrone sulfate potassium is applicable to breast cancer-related research[1][2][3][4].
Molekulargewicht:
388.52
Reinheit:
99.94
CAS Nummer:
[1240-04-6]
Formel:
C18H21KO5S
Target-Kategorie:
Endogenous Metabolite,Estrogen Receptor/ERR
Anwendungsbeschreibung:
MCE Product type: Natural Products
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