1-Methyladenine is a gonad maturation-promoting regulator. 1-Methyladenine is produced in testes and ovarian follicle cells of starfish under the induction of gonad-stimulating substance (GSS). 1-Methyladenine promotes starfish oocyte maturation and spawning, and modifies bases that regulate DNA structure. 1-Methyladenine converts T?A base pairs in double-stranded DNA into non-disruptive T (anti)?m1A (syn) Hoogsteen conformation. If this conformational base is not repaired in a timely manner, it transforms into cytotoxic DNA damage and blocks the replication process[1][2].
Molekulargewicht:
149.15
Reinheit:
99.99
CAS Nummer:
[5142-22-3]
Formel:
C6H7N5
Target-Kategorie:
Endogenous Metabolite
Anwendungsbeschreibung:
MCE Product type: Natural Products
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