15(S)-HPETE is a precursor of 15(S)-HETE (HY-113336). 15(S)-HPETE is a product of Arachidonic acid (HY-109590) in the 15-lipoxygenase pathway. 15(S)-HPETE reduces Bcl-2, Akt, and phosphorylated Akt protein levels. 15(S)-HPETE induces Apoptosis. 15(S)-HPETE antagonizes the angiogenic effects of 15(S)-HETE. 15(S)-HPETE exhibits antitumor effects against chronic myeloid leukemia. 15(S)-HPETE can be used in adipose tissue explant studies[1][2][3].
Molekulargewicht:
336.47
Reinheit:
97.32
CAS Nummer:
[70981-96-3]
Formel:
C20H32O4
Target-Kategorie:
Akt,Apoptosis,Bcl-2 Family,Drug Metabolite
Anwendungsbeschreibung:
MCE Product type: Reference compound
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