Cyclic GMP (cGMP) sodium, an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP sodium occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses[1][2][3][4].
Molekulargewicht:
367.19
Reinheit:
99.89
CAS Nummer:
[40732-48-7]
Formel:
C10H11N5NaO7P
Target-Kategorie:
Endogenous Metabolite
Anwendungsbeschreibung:
MCE Product type: Natural Products
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