Ageladine A (dihydrochloride), CAS [[2757574-06-2]] Preis auf Anfrage
Artikelnummer:
MCE-HY-113621B
Hersteller Artikelnummer:
HY-113621B
Alternativnummer:
MCE-HY-113621B-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Ageladine A dihydrochloride is an inhibitor of matrix metalloproteinase (MMP) isolated from the marine sponge Agelas nakamurai, possessing anti-angiogenic activity. Ageladine A dihydrochloride not only inhibits MMP-2 but also MMP-1, MMP-8, MMP-9, MMP-12, and MMP-13, with IC50 values of 4.65 µM, 2.79 µM, 907.12 nM, 1.83 µM, 767.57 nM, and 1.09 µM, respectively. Additionally, Ageladine A dihydrochloride is a pH-sensitive membrane-permeable dye that emits fluorescence in the blue-green range upon UV excitation, featuring a maximum absorption peak at 370 nm. Furthermore, Ageladine A dihydrochloride serves as a reliable and stable fluorescent pH sensor for detecting changes in intracellular pH values[1][2].
Molekulargewicht:
429.93
CAS Nummer:
[2757574-06-2]
Formel:
C10H9Br2Cl2N5
Target-Kategorie:
Fluorescent Dye,MMP
Anwendungsbeschreibung:
MCE Product type: Natural Products
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