(R)-Coriolic acid (13(R)-HODE) is the opposite enantiomer of the 13(S)-HODE produced when linoleic acid is incubated with soybean lipoxygenase. The presence of 13(R)-HODE in the supernatants and membranes of cultured bovine endothelial cells has been attributed to COX metabolism. 13(R)-HODE is a weak (IC50=2.7 µM) inhibitor of U-46619-induced platelet aggregation.
Molekulargewicht:
296.44
CAS Nummer:
[10219-69-9]
Formel:
C18H32O3
Target-Kategorie:
Endogenous Metabolite
Anwendungsbeschreibung:
MCE Product type: Reference compound
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