NCGC00092410 is a potent, selective, and nonsugar glucocerebrosidase (GC) inhibitor, with an IC50 of 31 nM. NCGC00092410 shows no activity against the related hydrolases at concentrations up to 77 µM. NCGC00092410, a GC chaperone, and increases the activity and lysosomal localization of glucocerebrosidase in mutant cell lines. NCGC00092410 can be used for the research of Gaucher disease[1].
Molekulargewicht:
353.46
Reinheit:
98.10
CAS Nummer:
[442898-34-2]
Formel:
C21H27N3O2
Target-Kategorie:
Glycosidase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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