Olutasidenib (FT-2102) is a highly potent, orally active, brain penetrant and selective inhibitor of mutant Isocitrate dehydrogenase 1 (IDH1), with IC50 values of 21.2 nM and 114 nM for IDH1- R132H and IDH1- R132C, respectively . Olutasidenib (FT-2102) is under the study in the treatment of acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) [1][2].
Molekulargewicht:
354.79
Reinheit:
99.16
CAS Nummer:
[1887014-12-1]
Formel:
C18H15ClN4O2
Target-Kategorie:
Isocitrate Dehydrogenase (IDH)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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