rel-PROTAC PARP1 degrader is the relative configuration of ROTAC PARP1 degrader (HY-114324). ROTAC PARP1 degrader is a PARP1 degrader based on MDM2 E3 ligand. It induces significant PARP1 cleavage and programmed cell death. PROTAC PARP1 degrader at 10 µM at 24 h inhibits MDA-MB-231 cell line with an IC50 of 6.12 µM.
Molekulargewicht:
1145.09
Reinheit:
98.99
Formel:
C58H63Cl2N11O10
Target-Kategorie:
PARP,PROTACs
Anwendungsbeschreibung:
MCE Product type: Reference compound
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