LEM-14, CAS [[1814881-70-3]]

Produktübersicht

• Artikelname: LEM-14, CAS [[1814881-70-3]]
• Artikelnummer: MCE-HY-114340
• Hersteller Artikelnummer: HY-114340
• Alternativnummer: MCE-HY-114340-50MG,MCE-HY-114340-10MG,MCE-HY-114340-10MMX1ML,MCE-HY-114340-5MG,MCE-HY-114340-100MG,MCE-HY-114340-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

LEM-14 is a potent and selective NSD2 inhibitor with an IC50 of 132 µM. LEM-14 has very weak activitv against NSD1 and has no activity against NSD3. LEM-14 inhibits fibrotic gene expression in ND but not DIO BMDMs. LEM-14 combined with ionizing radiation (IR) enhances the apoptosis rate and reduces the colony-formation ability of CRC cells. LEM-14 exhibits enhanced anti-tumor efficacy in Balb/c nude mice bearing LoVo cell xenografts when combined with ionizing radiation. LEM-14 has the potential for the research of multiple myeloma and colorectal cancer[1][2][3].

Produkteigenschaften

• Molekulargewicht: 478.56
• Reinheit: 98.02
• CAS Nummer: [1814881-70-3]
• Formel: C25H26N4O4S
• Target-Kategorie: Apoptosis,Histone Methyltransferase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound