FKBP12 PROTAC dTAG-13, CAS [[2064175-41-1]]

Produktübersicht

• Artikelname: FKBP12 PROTAC dTAG-13, CAS [[2064175-41-1]]
• Artikelnummer: MCE-HY-114421
• Hersteller Artikelnummer: HY-114421
• Alternativnummer: MCE-HY-114421-1MG,MCE-HY-114421-5MG,MCE-HY-114421-10MMX1ML,MCE-HY-114421-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: dTAG-13

Produktbeschreibung

FKBP12 PROTAC dTAG-13 (dTAG-13) is a FKBP12F36V PROTAC degrader and a PXR partial agonist. FKBP12 PROTAC dTAG-13 induces ubiquitination and proteasomal degradation of proteins tagged with FKBP12F36V, without degrading wild-type FKBP12 or un-fused PXR. It weakly promotes the recruitment of SRC-1, strongly inhibits the interaction between NCoR and PXR, and upregulates the expression of CYP3A4 and other drug metabolism-related genes. FKBP12 PROTAC dTAG-13 is applicable to research related to breast cancer and leukemia[1][2][3].

Produkteigenschaften

• Molekulargewicht: 1049.17
• Reinheit: 99.89
• CAS Nummer: [2064175-41-1]
• Formel: C57H68N4O15
• Target-Kategorie: FKBP,Pregnane X Receptor (PXR),PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound