Amquinate is a coccidiostat and a cytochrome b inhibitor. Amquinate blocks cytochrome-mediated electron transport near cytochrome b in mitochondria, acting downstream of coenzyme Q without affecting succinate dehydrogenase or NADH dehydrogenase. Amquinate inhibits succinate- and malate plus pyruvate-supported mitochondrial respiration in Eimeria tenella and does not affect L-ascorbate-supported respiration or any mitochondrial respiration in chicken liver mitochondria. Amquinate exhibits selective anticoccidial activity against wild-type Eimeria tenella. Amquinate can be used for the research of coccidiosis (Eimeria tenella infection)[1].
Molekulargewicht:
316.40
CAS Nummer:
[17230-85-2]
Formel:
C18H24N2O3
Target-Kategorie:
Mitochondrial Metabolism,Parasite
Anwendungsbeschreibung:
MCE Product type: Reference compound
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