BB-3497 is a potent, orally active and selective peptide deformylase (PDF) inhibitor. BB-3497 is highly selective for PDF (IC50 = 7 nM for E. coli PDF.Ni) over the other mammalian metalloenzymes (MMP-1/2/3/7 and enkephalinase). BB-3497 exhibits potent activity against gram-positive bacteria and some gram-negative pathogens. BB-3497 protects mice from infection in systemic models of Staphylococeus aureus. BB-3497 can be used for anti-bacterial infection research[1].
Molekulargewicht:
329.44
CAS Nummer:
[235784-88-0]
Formel:
C16H31N3O4
Target-Kategorie:
Antibiotic
Anwendungsbeschreibung:
MCE Product type: Natural Products
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