BRD4-IN-41, CAS [[1877286-69-5]] Preis auf Anfrage
Artikelnummer:
MCE-HY-115541
Hersteller Artikelnummer:
HY-115541
Alternativnummer:
MCE-HY-115541-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
BRD4-IN-41 is a BRD4 inhibitor with an IC50 of 34 nM. BRD4-IN-41 also inhibits JAK2, FLT3, RET, ROS1, NTRK3, PDGFRb, and FGFR1 kinases with IC50 values ranging from 0.9 nM to 43 nM. BRD4-IN-41 inhibits acetyl-lysine binding site of BRD4, downregulates c-MYC, reduces phosphorylated STAT3 levels, induces G1 cell cycle arrest and apoptosis, thereby inhibiting cancer cells growth. BRD4-IN-41 can be used for the research of cancer, such as multiple myeloma and acute myeloid leukemia[1].
