PptT-IN-1 (compound 5j) is a potent inhibitor of with phosphopantetheinyl phosphoryl transferase (PptT) an IC50 of 2.8 µM. Phosphopantetheinyl transferase, an essential enzyme that plays a critical role in the biosynthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. PptT-IN-1 has the potential for the research of tuberculosis[1].
Molekulargewicht:
347.46
Formel:
C18H29N5O2
Target-Kategorie:
Bacterial
Anwendungsbeschreibung:
MCE Product type: Reference compound
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