15-deoxy-delta12,14-Prostaglandin D2, CAS [[85235-11-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: 15-deoxy-delta12,14-Prostaglandin D2, CAS [[85235-11-6]] Preis auf Anfrage
• Artikelnummer: MCE-HY-116028
• Hersteller Artikelnummer: HY-116028
• Alternativnummer: MCE-HY-116028-1MG,MCE-HY-116028-1MG(2.99MMX1MLINMETHYLACETATE)
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: 15-Deoxy-delta12,14-PGD2

Produktbeschreibung

15-deoxy-delta12,14-Prostaglandin D2 (15-Deoxy-delta12,14-PGD2), a metabolite of PGD2 (HY-101988), is an agonist of prostaglandin receptor 2 (DP2). 15-deoxy-delta12,14-Prostaglandin D2 binds to DP2 (Ki=50 nM) and induces eosinophil activation (EC50=8 nM). 15-deoxy-delta12,14-Prostaglandin D2 also stimulates the recruitment of steroid receptor coactivator-1 (SRC-1) to peroxisome proliferator-activated receptor gamma (PPARgamma), inducing PPARgamma-mediated transcription. 15-deoxy-delta12,14-Prostaglandin D2 (15-Deoxy-delta12,14-PGD2) is cytotoxic to L1210 murine leukemia cells (IC50=0.3 µg/ml) and inhibits ADP-induced platelet aggregation (IC50=320 ng/mL).

Produkteigenschaften

• Molekulargewicht: 334.45
• Reinheit: 98
• CAS Nummer: [85235-11-6]
• Formel: C20H30O4
• Target-Kategorie: Endogenous Metabolite,PPAR,Prostaglandin Receptor,Src

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound