Trimethylamine N-oxide (Standard) is the analytical standard of Trimethylamine N-oxide. This product is intended for research and analytical applications. Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-beta/smad2 signaling pathway[1][2][3].
Molekulargewicht:
75.11
CAS Nummer:
[1184-78-7]
Formel:
C3H9NO
Target-Kategorie:
Drug Metabolite,Endogenous Metabolite,NOD-like Receptor (NLR),Reactive Oxygen Species (ROS),Reference Standards,TGF-beta/Smad
Anwendungsbeschreibung:
MCE Product type: Reference Standards
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