Trimethylamine-N-oxide-13C3 is the 13C-labeled Trimethylamine N-oxide. Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-beta/smad2 signaling pathway[1][2][3].
Molekulargewicht:
78.09
Formel:
13C3H9NO
Target-Kategorie:
Endogenous Metabolite,Isotope-Labeled Compounds,NOD-like Receptor (NLR),Reactive Oxygen Species (ROS),TGF-beta/Smad
Anwendungsbeschreibung:
MCE Product type: Isotope-Labeled Compounds
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