Tafetinib, CAS [[1032265-57-8]]
Artikelnummer:
MCE-HY-116116
| Artikelname: |
Tafetinib, CAS [[1032265-57-8]] |
| Artikelnummer: |
MCE-HY-116116 |
| Hersteller Artikelnummer: |
HY-116116 |
| Alternativnummer: |
MCE-HY-116116-5MG,MCE-HY-116116-1MG,MCE-HY-116116-10MG |
| Hersteller: |
MedchemExpress |
| Kategorie: |
Biochemikalien |
| Alternative Synonym: |
SIM010603 |
| Tafetinib (SIM010603) is an oral multi-targets receptor tyrosine kinases inhibitor. Tafetinib inhibitsstem cell factor receptor (Kit),vascular endothelial growth factor receptor-2 (VEGFR-2),platelet-derived growth factor receptor-beta (PDGFR-beta),glial cell line-derived neurotrophic factor receptor (Rearranged during Transfection, RET), andFms-like tyrosine kinase-3 (FLT3)withIC50values between 5.0 and 68.1 nmol/l. Tafetinib inhibits the phosphorylation ofPDGFR-betaandVEGFR-2. Tafetinib inhibits endothelial cell proliferation, endothelial cells chemotaxis, and corneal angiogenesis[1]. |
| Molekulargewicht: |
424.51 |
| Reinheit: |
96.20 |
| CAS Nummer: |
[1032265-57-8] |
| Formel: |
C24H29FN4O2 |
| Target-Kategorie: |
c-Kit,RET,VEGFR |
| Anwendungsbeschreibung: |
MCE Product type: Reference compound1 |
