Cipepofol (Ciprofol), a novel 2,6-disubstituted phenol derivative, is a positive allosteric modulator and direct agonist of the GABAA receptor. Cipepofol can cause the central nerve inhibition and promote sleep based on the structural modification of Propofol (HY-B0649). Cipepofol can activate the sirtuin1 (Sirt1)/Nrf2 pathway. Cipepofol protects the heart against Isoproterenol (ISO, HY-B0468)-induced myocardial infarction by reducing cardiac oxidative stress, inflammatory response and cardiomyocyte apoptosis[1][2].
Molekulargewicht:
204.31
Reinheit:
99.82
CAS Nummer:
[1637741-58-2]
Formel:
C14H20O
Target-Kategorie:
Apoptosis,GABA Receptor,Keap1-Nrf2,Sirtuin
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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