DU-14 is a potent steroid sulfatase inhibitor with an IC50 of 55.8 nM. DU-14 inhibits the MCF-7 cell proliferation (IC50 = 38.7 nM). DU-14 has neuroprotective effects against neurotoxic Abeta, suggesting that up-regulation of endogenous DHEAS by DU-14 could be beneficial to the alleviation of Abeta-induced impairments in spatial memory and synaptic plasticity[1][2][3].
Molekulargewicht:
426.61
Reinheit:
99.18
CAS Nummer:
[186303-55-9]
Formel:
C22H38N2O4S
Target-Kategorie:
Steroid Sulfatase
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
