TISCH is a potent and selective iodinated ligand with high affinity and selectivity for CNS D1 dopamine receptors. TISCH showed a Kd value of 0.205 nM in rat striatal tissue, indicating its effectiveness in biological activity. TISCH is able to easily cross the blood-brain barrier and show distribution in specific areas with D1 receptor density. TISCH is considered to be useful as a pharmacological tool for characterizing D1 dopamine receptors. When labeled with I-123, TISCH has the potential to be used as an in vivo imaging agent for CNS D1 dopamine receptors[1].
Molekulargewicht:
413.68
CAS Nummer:
[131615-52-6]
Formel:
C17H17ClINO
Target-Kategorie:
Dopamine Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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